Abstract
In this frontier article, we pursue the sequestration of radionuclides from aqueous solution by using recently emerging metal-organic framework (MOF) materials. The design of MOF materials and their corresponding sorption properties towards radionuclides (137Cs, 90Sr, 238U, 79Se, and 99Tc) as well as their interaction mechani**s are highlighted. The present challenges and future prospects of removing radionulides with MOFs as sorbents are also demonstrated.