, Strategy for Enhanced Antibacterial Activity against Staphylococus aureus by Assembly of Alamethicin with Thermo-Sensitive Polymeric Carrier, Chem. Commun., 2015, DOI: 10.1039/C5CC07054F
Abstract:
We demonstrate here a strategy for enhanced antibacterial activity against microbial strains by assembly of antimicrobial peptides with temperature-responsive polymeric carrier. The assembly complex was less toxic to human cells and more stable to enzymatic cleavage. This work may provide a promising drug delivery system for antimicrobial peptides.
