题目：Biodegradable Polymer Nanoparticles forMolecular Imaging

报告人：Kanyi Pu  教授

时间：11月24日（周五）上午09:30

地点：401号楼一楼A101会议室

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报告摘要：

Theconvergence of medicine and nanotechnology has been providing new opportunitiesto better understand fundamental biology, monitor health, perform diagnosis andtreat diseases. Semiconducting polymer nanoparticles (SPNs) transformed fromoptically and electrically active polymers have emerged as a new class ofoptical nanomaterials. As those polymers are completely organic andbiologically inert, SPNs essentially circumvent the issue of heavy metalion-induced toxicity to living organisms, possessing good biocompatibility. Inthis talk, I will present a new kind of biodegradable SPNs for ultrasensitivemolecular imaging. The potential clinical applications of these SPNs will bediscussed in imaging-guided surgery including lymph node mapping and tumor imaging.In addition, these nanoparticles can be developed into useful tools forreal-time in vivo evaluation of drug-induced hepatotoxicity, a long-standingconcern of modern medicine.

报告人简介：

Dr. KanyiPu has been an Associate Professor in the School of Chemical and BiomedicalEngineering (SCBE) at Nanyang Technological University since June 2015. He didhis MS (2007) with Prof. Wei Huang (CAS member) at Fudan University in China.He then came to Singapore and did his PhD (2011) at National University of Singapore.He moved to Stanford University School of Medicine for his postdoctoral studyin 2011, under the supervision of Prof. Jianghong Rao and the directorship ofProf. Sanjiv Sam Gambhir at the molecular imaging program at Stanford (MIPS).As an active member of MIPS and the Center for Cancer Nanotechnology Excellenceand Translation (CCNE-T), he made significant contributions to organic polymerbased imaging probes and technologies, such as photoacoustic imaging,chemiluminescence imaging and in vivo imaging of reactive oxygen and nitrogenspecies.

Dr. Pu has published more than 70 journalpapers, 2 book chapters and 6 patents. With a h-index of 40, his work has beenhighlighted by many world-renown scientific journals such as NatureBiotechnology, Nature Methods, and Cell Express el al. He also sits on theEditorial Board of Advanced Biosystems.