题目:Linking Biomolecules to Surfaces

报告人:Athena Guo教授

时间:0601日(周下午02:00

地点:401号楼三楼1305-1会议室

         欢迎广大师生踊跃参加!

                                                医学部欧洲杯官网

                                                放射医学及交叉学科研究院

报告摘要How does one link a biomolecule to a solid surface? Answers to this question are critical to a wide range of applications, including, among others, single molecule spectroscopy, biosensing, protein/peptide/antibody/DNA/glycan microarrays, biophysical analysis, microfluidics/biochips, nanoparticles for bioimaging or drug delivery. In this lecture, I will discuss proprietary technologies developed by MicroSurfaces over the past decade to provide superior surface coatings for biomolecular immobilization. In particular, I will introduce the ZeroBkg? polyethyleneglycol (PEG) brush technology which has been successfully adopted by thousands of scientists worldwide in turning novel ideas into breakthrough research results or efficient biochips/biosensors. I will introduce the Fluid Array technology based on fluidic and air-stable lipid bilayers. These mimicking cell membrane surfaces are finding successful applications in the screening and mechanistic study of cell surface interactions.

报告人简介:

Athena Guo, Ph.D, President/CEO, MicroSurfaces, Inc., New Jersey, USA.

She received his B.Sc. from Fudan University in 1984 and his PhD from University of Texas, Austin (USA) in 1992. She then obtained m-MBA from University of St. Thomas, Minneapolis (USA). She has over 20 years experience in academic/industrial research & business management, including two years as technical marketing representative for Bayer AG, eight years as research associate/research assistant professor at National Institute of Health, Washington University School of Medicine, and University of Minnesota, and 14 years as founder/president/CEO of MicroSurfaces, Inc. (http://proteinslides.com). In current position at MicroSurfaces, she has served as PI on 4 SBIR phase-I grants and 3 phase-II grants from NIH and NSF, and led the development and launch of MicroSurfaces’ two product lines–the ZeroBkg? surfaces for biomolecular immobilization and Fluid Array surfaces for membrane mimicking microarrays. These products have served thousands of scientists in world’s leading research laboratories, including academic, industrial, and government laboratories.