王畅，教授、硕士生导师
电子邮箱：wangchang[AT]suda.edu.cn
通讯地址：苏州工业园区仁爱路199号, 邮编215123
2006年3月于中国科学院大连化学物理研究所获得理学博士学位。2015.6-2016.6在美国加州大学戴维斯分校做访问学者，进行氧化脂类（oxylipin）的研究。2006年4月起至今于苏州大学工作，从事辐射损伤标志物以及临床疾病早期诊断以及药效评估的研究。先后主持国家自然基金项目2项，江苏省高校自然科学研究项目1项，参与国家自然科学基金联合基金重点支持项目1项。参与撰写研究专著两部。
学习简历：
1995-1999 年 陕西师范大学化学系本科
1999-2002 年 陕西师范大学化学系硕士（导师：章竹君教授）
2002-2006 年 中国科学院大连化学物理研究所（导师：许国旺研究员）
研究方向：
基于代谢组学和脂质组学的辐射损伤生物标志物研究
临床疾病早期诊断以及药效评估的研究
代表性论文：
1. Early metabolic characterization of brain tissues after whole body radiation based on gas chromatography-mass spectrometry in a rat model
Xueting Yao， Chao Xu，Yurong Cao， Lin Lin，Hanxu Wu，Chang Wang*
Biomed Chromatogr.2019, 33 (3): e4448.
2. Early metabolic characterization of brain tissues after whole body radiation based on gas chromatography-mass spectrometry in a rat model
Xueting Yao， Chao Xu，Yurong Cao， Lin Lin，Hanxu Wu，Chang Wang*
Biomed Chromatogr. 2018, doi: 10.1002/bmc.4448.
3. Monitoring tyrosine kinase inhibitor therapeutic responses with a panel of metabolic biomarkers in chronic myeloid leukemia patients
Bingyu Yang, Chang Wang#, Yiyu Xie, Liangjing Xu, Xiaojin Wu, Depei Wu
Cancer Sci. 2018, Cancer Sci, 109(3): 777-784.
4. Prediction of acute GVHD and relapse by metabolic biomarkers after allogeneic hematopoietic stem cell transplantation
Wu X, Xie Y, Wang C#, Han Y, Bao X, Ma S, Yilmaz A, Yang B, Ji Y, Xu J, Liu H, Chen S, Zhang J, Yu J, Wu D.
JCI Insight, 2018,3(9). pii: 99672. doi: 10.1172/jci.insight.99672
5. Urinary Metabolic Signatures and Early Triage of Acute Radiation Exposure in Rat Model
Mingxiao Zhao, Kim KT Lau, Xian Zhou, Jianfang Wu, Jun Yang, Chang Wang*
Molecular BioSystems, 2017, 13(4):756-766.
6. Asses**ent of early triage for acute radiation injury in rat model based on urinary amino acid target ****ysis
Yuanyuan Zhang, Xian Zhou, Chao Li, Jianfang Wu, John E. Kuo, Chang Wang*
Molecular BioSystems, 2014, 10(6): 1441-1449.
7. Quantification of amino acids in rat urine by solid phase extraction and liquid chromatography/electrospray tandem mass spectrometry: application to radiation injury rat model
Xinxing Tang, Yuan Gu, Jihua Nie, Saijun Fan, Chang Wang*
Journal of Liquid Chromatography & Related Technologies, 2014, 37(7): 951-973.
8. Estimation value of pla**a amino acid target ****ysis to the acute radiation injury early triage in the rat model
Xinxing Tang, Mingchen Zheng,Yuanyuan Zhang, Saijun Fan, Chang Wang*
Metabolomics, 2013 (9): 853-863.
9. Pla**a phospholipid metabolic profiling and biomarkers of rats following radiation exposure based on liquid chromatography–mass spectrometry technique
Chang Wang*, Yun Yang, Jihua Nie
Biomed.Chromatogr，2009, 23: 1079-1085.
10. Pla**a Phospholipid Metabolic Profiling and Biomarkers of Type 2 Diabetes Mellitus Based on High Performance Liquid Chromatography/Electrospray Mass Spectrometry and Multivariate Statistical Analysis
Chang Wang*, Hongwei Kong, Yufeng Guan, Jun Yang, Jianren Gu, Shengli Yang, Guowang Xu
Anal. Chem., 2005，77：4108-4116
