Jiao Yang, PhD, MD
Date of birth: 1977.11 Gender: Female
Associate Professor, School of Radiation Medicine and Protection, Soochow University,
Suzhou, Jiangsu, 215123, China
Tel: 86-512-65880052, Fax: 86-512-65880052
E-mail: jiaoyang@suda.edu.cn
Education Background:
PhD in Toxicology, Soochow University, China, 2007
MSc in Microbiology, Soochow University, China, 2004
MD in Clinical Medicine, Southeast University, China, 2001
Professional Experience:
2015--- : Research Scholar, Department of Pathology, Oklahoma University, USA
2010--- : Associate Professor, School of Radiation Medicine and Protection, Soochow University, China
2007---2010: Tutor, School of Radiation Medicine and Protection, Soochow University, China
2005---2007: Research Fellow, Department of Oncology, Georgetown University, USA.
Research Interests:
1. The Functions and Radio-sensitization of Tumor Suppressor Gene Tob1 in Cancer.
[1] Studies of biological functions and mechanisms of Tob1 in breast, ovarian, and lung cancer.
[2] Radio-sensitization of Tob1 in breast, ovarian, and lung cancer cell lines.
2. The Functions and Mechanisms of Long non-coding RNAs (lncRNAs) in IR induced DNA Damage .
[1] Investigation of the possibility of LncRNAs serving as a novel biological dosimeter of ionizing irradiation.
[2] The effects and mechanisms of LncRNAs in IR induced DNA damage.
Research Experience and Accomplishments:
I am an associate professor from Department of Radiation Genetics, School of Radiation Medicine and Protection of Soochow University, Jiangsu Province, PR China. After graduated from Soochow University and got the Ph.D. degree in 2007, I have been working in Soochow University. My research work is mainly about teaching (undergraduate students and graduate students) and doing scientific research. My current research focuses on (1) The functions and mechanisms of long non-coding RNAs in thoracic cancer therapy (project supported by the Natural Science Foundation of China, Granted No. 81302382 ); (2) The functions of antiproliferative gene Tob1 in cancer radiotherapy (supported by the Doctoral Fund of Ministry of Education, Granted No.20103201120016); (3) The development and screening of novel anti-cancer drugs etc..
As listed in my CV, from 2005 to 2007, I went to the Lombardi Comprehensive Cancer Center, Georgetown University at Washington DC in US, as Research fellow. Due to this experience, 10 year later Jiangsu Provincial Department of Education has approved my request to do research abroad. During this time, I will focus on anticancer properties and mechanisms of metal chelators as anticancer drugs and radiosensitizers in human carcinoma for one year. After that, I hope I can broaden my research work in radiation oncology on the basis of experience in previous studies and the experience at Oklahoma University.
Recent Publications:
1. Yang Jiao ，Chang Liu, Feng-mei Cui,Jia-ying Xu, Jian Tong, Xiao-fei Qi,Li-li Wang, Wei Zhu. Long intergenic non?coding RNA induced by X?ray irradiation pathwayregulates DNA damage response signaling in the human bronchial epithelial BEAS?2B cell line, ONCOLOGY LETTERS, 9(1):169-176,2015
2. KE-KANG SUN, NING ZHONG, YANG YANG, LIN ZHAO,YANG JIAO*. Enhanced radiosensitivity of NSCLC cells by transducer of erbB2.1 (TOB1) through modulation of the MAPK/ERK pathway. Oncology Reports. 29: 2385-2391, 2013 ( IF:2.297)
3. Jun CHE, Yan-wei LU, Chan FENG, Ai-jing DONG, Yang JIAO*. Overexpression of TOB1 confers radioprotection to bronchial epithelial cells through the MAPK/ERK pathway. Oncology Reports. 30: 637-642, 2013 (IF:2.297)
4. Yang Yang, Jiayi Dong, Kekang Sun, Lin Zhao, Fei Zhao, Lili Wang and Yang Jiao*. Obesity and incidence of lung cancer: A meta-analysis. International Journal of Cancer. 2012.132:1162-1169. (IF: 6.198)
5. Yang, Yang; Jiao, Yang*. Authors' reply to comments on a recent meta-analysis: Obesity and lung cancer. INTERNATIONAL JOURNAL OF CANCER, 2013.132(8), 1964-1965. (IF: 6.198)
6. Kekang Sun, Yang Yang, Lin Zhao, Lili Wang, Yang Jiao*. Transducer of erbB2.1 is a potential cellular target of gefitinib in lung cancer therapy. Oncology Letters. 2012. DOI: 10.3892/ol.2012.969. (IF: 0.987)
7. JIAO Yang, SUN Ke-kang, ZHAO Lin, XU Jia-ying, WANG Li-li,FAN Sai-jun*. Suppression of human lung cancer cell proliferation and metastasis in vitro by the transducer of ErbB-2.1(TOB1) [J]. Acta Pharmacol Sin. 2012,33(2): 250–260. (IF: 2.354)
8. JIAO Yang, GE Chun-min, MENG Qing-hui, CAO Jian-ping, TONG Jian, FAN Sai-jun*. Adenovirus-mediated expression of Tob1 sensitizes breast cancer cells to ionizing radiation. Acta Pharmacol Sin. 2007. 28(10): 1628-1636. (IF: 2.354)
9. JIAO Yang, WANG Hai-chao, FAN Sai-jun*. Growth suppression and radiosensitivity increase by HMGB1 in breast cancer. Acta Pharmacol Sin. 2007. 28(12): 1957-1967. (IF: 2.354)
10. JIAO Y, GE CM, MENG QH, CAO JP, TONG J, FAN SJ*. Dihydroartemisinin is an inhibitor of ovarian cancer cell growth. Acta Pharmacol Sin. 2007. 28(7): 1045-1056. (IF: 2.354)
11. Wang, Li-Li; Meng, Qing-Hui; Jiao, Yang; Xu, Jia-Ying; Ge, Chun-Min; Zhou, Ju-Ying; Rosen, Eliot M.; Wang, Hai-Chao; *Fan, Sai-Jun. High-Mobility Group Boxes Mediate Cell Proliferation and Radiosensitivity via Retinoblastoma-Interaction-Dependent and -Independent Mechanisms. Cancer Biotherapy and Radiopharmaceuticals, 2012, 27(5): 329-335. (IF: 1.381)
12. Li, Zheng; Qiu, Hui-Ying; Jiao, Yang; Cen, Jian-Nong; Fu, Chun-Mei; Hu, Shao-Yan; Zhu, Ming-Qing; Wu, De-Pei; *Qi, Xiao-Fei. Growth and Differentiation Effects of Homer3 on a Leukemia Cell Line. ASIAN PACIFIC JOURNAL OF CANCER PREVENTION. 2013, 14(4), 2525-2528. (IF:1.5 )
13. Hu, Xu-Dong; Meng, Qing-Hui; Xu, Jia-Ying; Jiao, Yang; Ge, Chun-Min; Jacob, Asha; Wang, Ping; Rosen, Eliot M.; *Fan, Saijun. BTG2 is an LXXLL-dependent co-repressor for androgen receptor transcriptional activity. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2011, 404(4), 903-909. (IF: 2.281)
14. Xu, Jia-Ying; Meng, Qing-Hui; Chong, Yu; Jiao, Yang; Zhao, Lin; *Rosen, Eliot M.; Fan, Saijun. Sanguinarine inhibits growth of human cervical cancer cells through the induction of apoptosis. ONCOLOGY REPORTS. 2012, 28(6), pp 2264-2270. (IF:2.297 )
Honors and Awards:
2012: The Third Prizes (rank second), The 2012 Annual Shandong Medical Science and Technology Award.
2007: The Third Prizes, the 10th National Challenge Cup Competition for Academic and Scientific Achievements among University Students.
Contact Information：
School of Radiation Medicine and Protection, Soochow University，
Room 2305, BLDG 402, No.199 Renai Rd, Suzhou, Jiangsu, 215123, China
Tel: 86-512-65880052, Fax: 86-512-65880052
E-mail: jiaoyang@suda.edu.cn