俞家华，副教授，硕士生导师
电话：0512-65880065
传真：0512-65884380
电子邮箱：yujiahua@suda.edu.cn
通讯地址：苏州市工业园区仁爱路199号402-2319，215123
个人简介
俞家华，2004年毕业于苏州大学放射医学专业，获得医学学士学位，后赴韩国国立全北大学攻读研究生，于2010年获得医学博士学位。2011年至今在苏州大学医学部欧洲杯官网放射生物学教研室任教，主持国家自然科学青年基金一项，江苏省高校自然科学研究面上项目一项，以通讯作者和第一作者发表SCI期刊论文12篇。
研究方向
放射性肺损伤机制和防治
肿瘤辐射增敏
电离辐射诱导DNA损伤机制
科研项目
1. 国家自然科学基金青年项目，脂肪干细胞治疗放射性肺损伤及其机制研究（81202149），2013/01-2015/12，负责人。
2. 江苏省高校自然科学研究面上项目，IL-6介导的STAT3通路参与放射性肺炎发病的机制研究（13KJB310016），2013/08-2015/12，负责人。
代表性论著
1. Jie Du, JunShang, Fei Chen, Shuyu Zhang, Narui Yin, Ting Xie, Haowen Zhang, Jiahua Yu*, Fenju Liu*, A CRISPR/Cas9-based screening for non-homologous end joining inhibitors reveals ouabain and penfluridol as radiosensitizers. Mol Cancer Ther. 2017, doi: 10.1158/1535-7163.MCT-17-0090.
2. Song Hua#, Jiahua Yu#, Jun Shang, Haowen Zhang, Jie Du, Yushuo Zhang, Fei Chen, Yuan Zhou, Fenju Liu*. Effective tumor-targeted delivery of etoposide using chitosan nanoparticles conjugated with folic acid and sulfobetaine methacrylate, RSC Advances 2016, 6(94): 91192-91200。
3. Jiahua Yu*, Xiaopeng Yuan, Yang Liu, Kaishuo Zhang, Jie Wang, Haowen Zhang, Fenju Liu*. Delayed administration of WP1066, an STAT3 inhibitor, ameliorates radiation-induced lung injury in mice, Lung 2016, 194(1): 67-74.
4. Xiaopeng Yuan#, Jie Du#, Song Hua, Haowen Zhang, Cheng Gu, Jie Wang, Lei Yang, Jianfeng Huang, Jiahua Yu*, Fenju Liu*. Suppression of autophagy augments the radiosensitizing effects of STAT3 inhibition on human glioma cells. Experimental Cell Research, 2015, 330(2): 267-276.
5. Jie Wang, Xiaopeng Yuan, Cheng Gu, Jianfeng Huang, Jiahua Yu*, Fenju Liu*. Pretreatment of gelsolin antibody aggravates radiation-induced lung injury in mice. Nuclear Science and Techniques 2014, 25,020301.
6. Jiahua Yu, Sun-O Ka, Kang-Beom Kwon, Sang-Myeong Lee, Jin-Woo Park, and Byung-Hyun Park*. Overexpression of the small GTPase Arl4d suppresses adipogenesis. Int J Mol Med 2011; 28(5):793-798.
7. Ikjae Lee#, Jiahua Yu#, Yesie Yoon, Hyo Jin Gim, Sang-Myeong Lee, Jin-Woo Park, Roak Jeon, and Byung-Hyun Park. [5-(3-Indol-1-ylpropoxy)-1H-indol-3-yl] acetic acid enhances adipocyte differentiation and glucose uptake in 3T3-L1 cells. International Journal of Pharmacology 2011; 7(5):647-652.
8. Jiahua Yu, Hwa-Suk Lee, Sang-Myeong Lee, Hee-Chul Yu, Woo Sung Moon, Myoung Ja Chung, Jin-Woo Park, and Byung-Hyun Park*. Aggravation of post-ischemic liver injury by overexpression of A20, an NF-κB suppressor. J Hepatol 2011; 55(2): 328-336.
9. Kuichang Yuan#, Jiahua Yu#, Amin Shah, Shan Gao, Sun Young Kim, Sung Zoo Kim, Byung-Hyun Park, and Suhn Hee Kim. Leptin reduces plasma ANP levels via nitric oxide dependent mechanism. Am J Physiol Regul Integr Comp Physiol 2010; 298(4): R1007-R1016.
10. Jiahua Yu, Kang-Beom Kwon, Jin-Woo Park, Han-Jung Chae, and Byung-Hyun Park. Bax inhibitor-1 overexpression reduces the suppressive effect of calcium mobilizing agent on adipogenesis. Int J Biochem Cell Biol 2009; 41(8-9):1739-1745.
11. Jiahua Yu, Hee-Chul Yu, Kyung-Ah Kim, Kang-Beom Kwon, Jin-Woo Park, Sung-Zoo Kim, Suhn Hee Kim, and Byung-Hyun Park. Differences in the amount of lipolysis induced by atrial natriuretic peptide in small and large adipocytes. J Pept Sci 2008; 14(8): 972-977.
12. Jiahua Yu, Yeon Jun Jeong, Kang-Beom Kwon, Sung-Zoo Kim, Suhn Hee Kim, Jin-Woo Park, Hee-Chul Yu, and Byung-Hyun Park. A comparison of the lipolytic activity of different natriuretic peptides on human adipocytes. Int J Pept Res Ther 2008; 14: 167-172.
授权发明专利
俞家华，刘芬菊，袁小鹏，顾成，王洁，杨磊，一种检测间充质干细胞分布的方法，2015.02.18，中国，ZL201310189450.5
课程教学及招生信息
课程教学及招生信息
放射生物学（研究生，本科生课程）